Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394270 | 1.00 | DHODH (0.45) | DHODHALDH1A1SMN1; SMN2PKML3MBTL1 | |
| SCHEMBL9759151 | 0.80 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2PKML3MBTL1KDM4E | |
| SCHEMBL9550214 | 0.79 | NPC1 (0.62) | L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL9193731 | 0.79 | NPC1 (0.62) | L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL9550244 | 0.78 | SMN1; SMN2 (0.38) | DHODHALDH1A1SMN1; SMN2PKML3MBTL1 | |
| SCHEMBL9196621 | 0.78 | SMN1; SMN2 (0.38) | DHODHALDH1A1SMN1; SMN2PKML3MBTL1 | |
| SCHEMBL9586849 | 0.76 | ALDH1A1 (0.49) | DHODHALDH1A1SMN1; SMN2KDM4EALOX5 | |
| SCHEMBL9364842 | 0.76 | ALDH1A1 (0.49) | DHODHALDH1A1SMN1; SMN2KDM4EALOX5 | |
| SCHEMBL9191559 | 0.73 | ALOX15 (0.34) | DHODHALDH1A1L3MBTL1KDM4EPTGDR2 | |
| SCHEMBL9163369 | 0.73 | CNR1 (0.45) | SMN1; SMN2L3MBTL1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968709-A | AGRICULTURE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | claimed |