Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 2/20 | 0.37 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 2/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.32 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.31 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394925 | 0.88 | TYMP (0.38) | TYMPSLC6A11SLC6A1HPGDTP53 | |
| SCHEMBL10394332 | 0.82 | TYMP (0.54) | TYMPSLC6A11SLC6A1HPGDTP53 | |
| SCHEMBL10706957 | 0.79 | TYMP (0.35) | TYMPSLC6A11SLC6A1HPGDSLC6A12 | |
| SCHEMBL10760950 | 0.72 | TYMP (0.33) | TYMPSLC6A11SLC6A1HPGD | |
| SCHEMBL23630131 | 0.70 | TYMP (0.72) | TYMP | |
| SCHEMBL20579728 | 0.70 | TYMP (0.72) | TYMP | |
| SCHEMBL10394454 | 0.69 | TYMP (0.44) | TYMPSLC6A11SLC6A1HPGDMEN1 | |
| SCHEMBL10696433 | 0.69 | TYMP (0.41) | TYMPSLC6A11SLC6A1TP53SLC6A12 | |
| SCHEMBL10394453 | 0.69 | TYMP (0.44) | TYMPSLC6A11SLC6A1HPGDMEN1 | |
| SCHEMBL7867925 | 0.65 | CCNB2 (0.39) | TYMPHPGDMEN1KMT2API4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968674-A | Antiviral carbocyclic purine nucleosides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-11-06 | — | — | US | disclosed |
| EP-0236935-A2 | Carboxylic purine nucleosides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-16 | — | — | EP | disclosed |