Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867778 | 0.82 | CCNB2 (0.38) | CCNB2CDK1CCNB1CCNB3KIF11 | |
| SCHEMBL14175360 | 0.70 | CDK1 (0.48) | CCNB2CDK1CCNB1CCNB3EGFR | |
| SCHEMBL14175378 | 0.70 | CCNB2 (0.46) | CCNB2CDK1CCNB1CCNB3KIF11 | |
| SCHEMBL9583386 | 0.70 | CDK1 (0.44) | CCNB2CDK1CCNB1CCNB3MEN1 | |
| SCHEMBL29964989 | 0.69 | KIF11 (0.50) | KIF11MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29964869 | 0.68 | KIF11 (0.47) | KIF11MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9583072 | 0.68 | CCNB2 (0.42) | CCNB2CDK1CCNB1CCNB3HPGD | |
| SCHEMBL2111739 | 0.68 | TYMP (0.48) | ADORA2AADORA2BTYMP | |
| SCHEMBL7872820 | 0.68 | HDAC1 (0.48) | CCNB2CDK1CCNB1CCNB3HPGD | |
| SCHEMBL14175383 | 0.68 | CDK1 (0.44) | CCNB2CDK1CCNB1CCNB3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316595-B1 | PNA synthesis using a base-labile amino protecting group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6121418-A | PNA synthesis using a base-labile amino protecting group | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |