Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.44 |
| ▸ | XDH | P47989 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394454 | 1.00 | TYMP (0.44) | TYMPXDHHPGDPNPMEN1 | |
| SCHEMBL10696433 | 0.89 | TYMP (0.41) | TYMPXDHMEN1KMT2ASLC6A1 | |
| SCHEMBL10394457 | 0.82 | PNP (0.40) | TYMPXDHPNPMEN1KMT2A | |
| SCHEMBL10394925 | 0.81 | TYMP (0.38) | TYMPHPGDMEN1KMT2ASLC6A1 | |
| SCHEMBL10394456 | 0.80 | SLC6A11 (0.36) | TYMPMEN1KMT2ASLC6A1HPRT1 | |
| SCHEMBL30631035 | 0.79 | TYMP (0.43) | TYMPXDHHPGDPNPMEN1 | |
| SCHEMBL7897645 | 0.76 | TYMP (0.50) | TYMPXDHHPGDPNPMEN1 | |
| SCHEMBL10394332 | 0.76 | TYMP (0.54) | TYMPXDHHPGDMEN1KMT2A | |
| SCHEMBL16401943 | 0.75 | TYMP (0.49) | TYMPXDHHPGDMEN1KMT2A | |
| SCHEMBL30898731 | 0.75 | TYMP (0.51) | TYMPXDHHPGDADORA3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968674-A | Antiviral carbocyclic purine nucleosides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-11-06 | — | — | US | disclosed |
| EP-0236935-A2 | Carboxylic purine nucleosides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-16 | — | — | EP | disclosed |