Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.31 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394333 | 0.82 | TYMP (0.46) | TYMPADORA3ALDH1A1BACE1 | |
| SCHEMBL10394331 | 0.82 | TYMP (0.37) | TYMPSLC6A11SLC6A1HPGDMEN1 | |
| SCHEMBL10394926 | 0.79 | TYMP (0.51) | TYMPADORA3ALDH1A1HPRT1 | |
| SCHEMBL10759491 | 0.79 | TYMP (0.49) | TYMPMAPTPKMSLC6A11SLC6A1 | |
| SCHEMBL10394454 | 0.76 | TYMP (0.44) | TYMPSLC6A11SLC6A1ADORA3XDH | |
| SCHEMBL10394453 | 0.76 | TYMP (0.44) | TYMPSLC6A11SLC6A1ADORA3XDH | |
| SCHEMBL12515629 | 0.72 | TYMP (0.68) | TYMPMAPTPKMALDH1A1CYP1A2 | |
| SCHEMBL10696433 | 0.72 | TYMP (0.41) | TYMPSLC6A11SLC6A1XDHMEN1 | |
| SCHEMBL10394925 | 0.71 | TYMP (0.38) | TYMPMAPTSLC6A11SLC6A1ALDH1A1 | |
| SCHEMBL29673058 | 0.71 | TYMP (0.87) | TYMPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968674-A | Antiviral carbocyclic purine nucleosides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-11-06 | — | — | US | disclosed |