Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 8/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1040507 | 0.92 | THRB (0.33) | RORCMAPTTP53REN | |
| SCHEMBL1037811 | 0.91 | REN (0.33) | PIK3CDPIK3CARORCMAPTTP53 | |
| SCHEMBL1040351 | 0.87 | REN (0.35) | PIK3CDPIK3CAMAPTREN | |
| SCHEMBL3942761 | 0.86 | RORC (0.34) | PIK3CDPIK3CARORCMAPTTP53 | |
| SCHEMBL1038354 | 0.85 | REN (0.36) | PIK3CDPIK3CARORCMAPTREN | |
| SCHEMBL1039437 | 0.84 | AXL (0.36) | PIK3CDPIK3CARORCMAPTTP53 | |
| SCHEMBL1039533 | 0.84 | RORC (0.33) | RORCRENNPY5R | |
| SCHEMBL1037899 | 0.83 | REN (0.31) | REN | |
| SCHEMBL1037898 | 0.83 | REN (0.31) | REN | |
| SCHEMBL1038043 | 0.83 | RORC (0.32) | RORCREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049514-B1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2011-01-26 | — | — | EP | disclosed |