Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619652 | 0.80 | KDM4E (0.48) | ALDH1A1LMNAHTTHPGDSMN1; SMN2 | |
| SCHEMBL28641102 | 0.77 | HTT (0.53) | ALDH1A1NPSR1LMNAHTTHPGD | |
| SCHEMBL10395711 | 0.77 | PIK3CD (0.38) | PIK3CD | |
| SCHEMBL28640929 | 0.72 | KDM4E (0.59) | ALDH1A1LMNAHTTTSHRHPGD | |
| SCHEMBL7531287 | 0.72 | ALDH1A1 (0.64) | ALDH1A1NPSR1LMNAHTTTSHR | |
| SCHEMBL28630449 | 0.71 | ALDH1A1 (0.62) | ALDH1A1NPSR1LMNAHTTTSHR | |
| SCHEMBL10395650 | 0.70 | ALDH1A1 (0.51) | ALDH1A1NPSR1LMNAHTTTSHR | |
| SCHEMBL8973821 | 0.67 | HTT (0.63) | ALDH1A1NPSR1LMNAHTTHPGD | |
| SCHEMBL19111287 | 0.66 | KMT2A (0.53) | ALDH1A1NPSR1LMNAHTTTSHR | |
| SCHEMBL10395758 | 0.66 | PIK3CD (0.31) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906751-A | Mercaptotriazine derivatives as lubricant additives | CIBA-GEIGY CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0317513-A2 | Mercaptotriazine derivatives as lubricant additives | CIBA-GEIGY AG (CH) | 1989-05-24 | — | — | EP | disclosed |