SCHEMBL7619652

SCHEMBL7619652

Sc1nc(S)nc(N2CCOCC2)n1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.48
HTT P42858 3/20 0.48
MAPK1 P28482 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KMT2A Q03164 2/20 0.47
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 3/20 0.46
LMNA P02545 2/20 0.46
GAA P10253 2/20 0.46
PIK3R1 P27986 2/20 0.44
PIK3CA P42336 2/20 0.44
MTOR P42345 2/20 0.44
HPGD P15428 2/20 0.43
POLB P06746 1/20 0.43
MEN1 O00255 1/20 0.42
GLA P06280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28641102 0.95 HTT (0.53) KDM4EHTTMAPK1SMN1; SMN2KMT2A
SCHEMBL28640929 0.90 KDM4E (0.59) KDM4EHTTMAPK1SMN1; SMN2ALDH1A1
SCHEMBL28630449 0.88 ALDH1A1 (0.62) KDM4EHTTMAPK1SMN1; SMN2KMT2A
SCHEMBL8973821 0.83 HTT (0.63) KDM4EHTTMAPK1SMN1; SMN2KMT2A
SCHEMBL10395652 0.80 ALDH1A1 (0.52) HTTMAPK1SMN1; SMN2KMT2AALDH1A1
SCHEMBL9418611 0.80 HTT (0.61) KDM4EHTTMAPK1SMN1; SMN2KMT2A
SCHEMBL8629697 0.78 HRH1 (0.50) HTTMAPK1SMN1; SMN2KMT2AALDH1A1
SCHEMBL7531287 0.78 ALDH1A1 (0.64) KDM4EHTTMAPK1SMN1; SMN2KMT2A
SCHEMBL10816947 0.76 SMN1; SMN2 (0.52) KDM4EHTTMAPK1SMN1; SMN2KMT2A
SCHEMBL29274357 0.73 HRH1 (0.56) KDM4EHTTMAPK1SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118745246-A High refractive material based on biomass magnolol and honokiol 中国科学院上海有机化学研究所 2024-10-08 CN claimed
US-20230101743-A1 SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF MUSC FOUNDATION FOR RESEARCH DEVELOPMENT 2023-03-30 US claimed
EP-4087837-A1 SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF Musc Foundation for Research Development (US) 2022-11-16 EP claimed
WO-2021141984-A1 SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2021-07-15 WO claimed
CN-118745246-A High refractive material based on biomass magnolol and honokiol 中国科学院上海有机化学研究所 2024-10-08 CN disclosed
US-20230101743-A1 SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF MUSC FOUNDATION FOR RESEARCH DEVELOPMENT 2023-03-30 US disclosed
EP-4087837-A1 SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF Musc Foundation for Research Development (US) 2022-11-16 EP disclosed
WO-2021141984-A1 SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2021-07-15 WO disclosed
WO-2021141984-A1 SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2021-07-15 WO disclosed
CN-112480363-A Xylylene diisocyanate composition, xylylene diisocyanate modified product composition, two-pack type resin raw material, and resin 三井化学株式会社 2021-03-12 CN disclosed
CN-112480364-A Xylylene diisocyanate composition, xylylene diisocyanate modified product composition, two-pack type resin raw material, and resin 三井化学株式会社 2021-03-12 CN disclosed
CN-112409566-A Xylylene diisocyanate composition, xylylene diisocyanate modified product composition, two-pack type resin raw material, and resin 三井化学株式会社 2021-02-26 CN disclosed
CN-1041917-C Polythiol, process for producing the same, sulfur-containing polyurethane-based resin obtained therefrom, process for producing the same, and lens MITSUI CHEMICALS INC (JP) 1999-02-03 CN disclosed
EP-0508390-B1 Light-sensitive silver halide photographic material KONISHIROKU PHOTO IND (JP) 1998-07-01 EP disclosed
CN-1111619-A Polythiol, process for producing the same, sulfur-containing polyurethane-based resin obtained therefrom, process for producing the same, and lens MITSUI TOATSU CHEMICALS (JP) 1995-11-15 CN disclosed
US-5258280-A 2-amino-4,6-dimercapto-1,3,5-triazine derivatives; blackness, high covering power KONICA CORPORATION (JP) 1993-11-02 US disclosed
EP-0508390-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1992-10-14 EP disclosed
US-4173694-A A DI OR TRI-MERCAPTO-S-TRIAZINE VULCANIZING AGENT AND A POLYALKYLENE POLYAMINE PROMOTER AND ANTICORROSION AGENT NIPPON ZEON CO., LTD. (JP) 1979-11-06 US disclosed
US-4105627-A MERCAPTOHETEROCYCLIC RESIN STABILIZERS ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US disclosed
US-3969349-A Vulcanization of rubber with phosphoro triazine sulfides MONSANTO COMPANY (US) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230101743-A1 SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF PCSK9, SLC10A1, CYP3A5 KDM4E 2992/4885HTT 888/4885MAPK1 2752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.