SCHEMBL10396166

SCHEMBL10396166

O=Cc1cc2c3c(c1)CCCN3CC=C2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.39
KMT2A Q03164 6/20 0.39
MEN1 O00255 4/20 0.39
MAPT P10636 4/20 0.39
HPGD P15428 3/20 0.39
GAA P10253 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.35
RAD52 P43351 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
TRIM24 O15164 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
ALDH1A3 P47895 4/20 0.33
KDM4E B2RXH2 4/20 0.33
RECQL P46063 3/20 0.32
TDP1 Q9NUW8 3/20 0.32
POLB P06746 2/20 0.32
BLM P54132 2/20 0.32
GFER P55789 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CES1 P23141 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3740292 0.79 TRIM24 (0.31) ALDH1A1TRIM24TRIM33ALDH1A3
SCHEMBL254935 0.79 KMT2A (0.50) ALDH1A1KMT2AMEN1MAPTHPGD
SCHEMBL13500398 0.77 KMT2A (0.36) ALDH1A1KMT2AMEN1RAD52RXFP1
SCHEMBL4869823 0.76 KMT2A (0.48) ALDH1A1KMT2AMEN1MAPTHPGD
SCHEMBL3333311 0.71 HTR2C (0.46) ALDH1A1KMT2AMEN1HPGDSMN1; SMN2
SCHEMBL2839306 0.68 ALDH1A1 (0.45) ALDH1A1KMT2AMEN1MAPTHPGD
SCHEMBL13989159 0.64 KMT2A (0.53) ALDH1A1KMT2AMEN1MAPTHPGD
SCHEMBL15882809 0.64 KMT2A (0.45) ALDH1A1KMT2AMEN1MAPTHPGD
SCHEMBL15882807 0.64 KMT2A (0.45) ALDH1A1KMT2AMEN1MAPTHPGD
SCHEMBL23235276 0.62 ALDH1A1 (0.66) ALDH1A1KMT2AMEN1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101121714-B Method for synthesizing 3-(2-phenylethyl)-5-[2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolin-en]-2,4-oxazolidinedione NINGBO INST TECH ZHEJIANG UNIV 2011-06-22 CN disclosed
CN-101121714-A Method for synthesizing 3-(2-phenylethyl)-5-[2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolin-en]-2,4-oxazolidinedione NINGBO INST OF TECHNOLOGY (CN) 2008-02-13 CN disclosed
US-4940654-A Solid particle dispersion filter dyes for photographic compositions EASTMAN KODAK COMPANY (US) 1990-07-10 US disclosed
EP-0068876-A1 Oxoindolizine and oxoindolizinium dyes and processes for their preparation EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-01-05 EP disclosed
US-RE30235-E FOR ELECTROPHORETIC MIGRATION IMAGING PROCESSES EASTMAN KODAK COMPANY (US) 1980-03-18 US disclosed
US-4012376-A Photosensitive colorant materials EASTMAN KODAK COMPANY (US) 1977-03-15 US disclosed