SCHEMBL254935

SCHEMBL254935

O=Cc1cc2c3c(c1)CCCN3CCC2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.50
MEN1 O00255 6/20 0.50
RAD52 P43351 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
ALDH1A1 P00352 13/20 0.49
MAPT P10636 7/20 0.49
HPGD P15428 5/20 0.49
GAA P10253 4/20 0.49
TRIM24 O15164 1/20 0.47
TRIM33 Q9UPN9 1/20 0.47
KDM4E B2RXH2 6/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
POLB P06746 3/20 0.44
RECQL P46063 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
BLM P54132 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
GFER P55789 1/20 0.44
ALDH1A3 P47895 5/20 0.41
LMNA P02545 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4869823 0.96 KMT2A (0.48) KMT2AMEN1RAD52RXFP1ALDH1A1
SCHEMBL13989159 0.83 KMT2A (0.53) KMT2AMEN1RAD52RXFP1ALDH1A1
SCHEMBL2839306 0.82 ALDH1A1 (0.45) KMT2AMEN1RAD52RXFP1ALDH1A1
SCHEMBL15882807 0.82 KMT2A (0.45) KMT2AMEN1RAD52RXFP1ALDH1A1
SCHEMBL15882809 0.82 KMT2A (0.45) KMT2AMEN1RAD52RXFP1ALDH1A1
SCHEMBL15267534 0.80 KMT2A (0.50) KMT2AMEN1RAD52RXFP1ALDH1A1
SCHEMBL10396166 0.79 ALDH1A1 (0.39) KMT2AMEN1RAD52RXFP1ALDH1A1
SCHEMBL13989158 0.78 KMT2A (0.49) KMT2AMEN1RAD52RXFP1ALDH1A1
SCHEMBL14366795 0.78 KMT2A (0.49) KMT2AMEN1RAD52RXFP1ALDH1A1
SCHEMBL7602627 0.77 KMT2A (0.47) KMT2AMEN1RAD52RXFP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 674 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118534063-A Kit and method for rapidly detecting heavy metal mercury silver in grains 南京财经大学 2024-08-23 CN claimed
EP-1778176-B1 COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL AG & CO KGAA (DE) 2012-07-25 EP claimed
US-7413579-B2 Method for dyeing fibers containing keratin HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-19 US claimed
EP-1432388-B1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL AG & CO KGAA (DE) 2008-06-18 EP claimed
EP-1909913-A1 METHOD FOR QUICKLY CONCEALING THE ROOTS OF HAIR THAT HAVE GROWN AFTER THE HAIR HAS BEEN DYED HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-04-16 EP claimed
EP-1858476-A1 METHOD FOR INCREASING THE COLOR INTENSITY OF COLORATIONS ON KERATIN-CONTAINING SUBSTRATES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-11-28 EP claimed
US-7300472-B2 Agents for coloring fibers containing keratin HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-11-27 US claimed
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
EP-1778176-A2 MEANS FOR COLOURING KERATIN-CONTAINING FIBRES Henkel Kommanditgesellschaft auf Aktien (DE) 2007-05-02 EP claimed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US claimed
WO-2003030845-A1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
WO-2003030847-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-1300133-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
EP-1200051-A1 AGENT FOR DYING KERATIN FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2002-05-02 EP claimed
WO-2001013866-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-03-01 WO claimed
US-6017660-A PIGMENTED INK COMPRISING ADDITION POLYMER MONOMER, PHOTOINITATOR MIXTURE CONTAINING A DIARYLIODONIUM SALT, SENSITIZER FOR 2-METHYL-4,6-BIS(TRICHLOROMETHYL)-S-TRIAZINE, AND ELECTRON DONOR COMPOUND; PHOTOCURABLE 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-01-25 US claimed
US-5545676-A CURING MORE RAPIDLY AND DEEPLY UNDER UV OR VISIBLE LIGHT USING AN ARYLIODONIUM SALT, A PHOTOSENSITIZER AND AN ELECTRON DONOR; DENTAL ADHESIVE; PHOTORESISTS; BINDER FOR ABRASIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-13 US claimed
US-4709107-A Process for producing nitrones GENERAL ELECTRIC COMPANY (US) 1987-11-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 KMT2A 927/4885MEN1 2976/4885RAD52 1232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.