Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | BLM | P54132 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 4/20 | 0.35 |
| ▸ | RECQL | P46063 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837705 | 0.91 | ALDH1A1 (0.39) | ALDH1A1KMT2AMAPTMEN1HPGD | |
| SCHEMBL254935 | 0.82 | KMT2A (0.50) | ALDH1A1KMT2AMAPTMEN1HPGD | |
| SCHEMBL4869823 | 0.79 | KMT2A (0.48) | ALDH1A1KMT2AMAPTMEN1HPGD | |
| SCHEMBL4698664 | 0.70 | ALDH1A1 (0.35) | ALDH1A1KMT2AMAPTMEN1HPGD | |
| SCHEMBL2846045 | 0.70 | HTR2C (0.49) | ALDH1A1KMT2AMAPTMEN1HPGD | |
| SCHEMBL13989159 | 0.68 | KMT2A (0.53) | ALDH1A1KMT2AMAPTMEN1HPGD | |
| SCHEMBL10396166 | 0.68 | ALDH1A1 (0.39) | ALDH1A1KMT2AMAPTMEN1HPGD | |
| SCHEMBL15882807 | 0.67 | KMT2A (0.45) | ALDH1A1KMT2AMAPTMEN1HPGD | |
| SCHEMBL15882809 | 0.67 | KMT2A (0.45) | ALDH1A1KMT2AMAPTMEN1HPGD | |
| SCHEMBL15267534 | 0.65 | KMT2A (0.50) | ALDH1A1KMT2AMAPTMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046190-A2 | TRICYCLIC ALDEHYDES AND C,H ACIDIC COMPOUNDS | HENKEL AG & CO. KGAA (DE) | 2010-04-29 | — | — | WO | claimed |
| WO-2010046190-A2 | TRICYCLIC ALDEHYDES AND C,H ACIDIC COMPOUNDS | HENKEL AG & CO. KGAA (DE) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046190-A2 | TRICYCLIC ALDEHYDES AND C,H ACIDIC COMPOUNDS | HENKEL AG & CO. KGAA (DE) | 2010-04-29 | — | — | WO | disclosed |
| US-6844089-B2 | Organic red electro-luminescent device and dopant | SENSIENT IMAGING TECHNOLOGIES GMBH (DE) | 2005-01-18 | — | — | US | disclosed |
| US-20050010048-A1 | Aza-and polyaza-naphthalenly ketones useful as hiv integrase inhibitors | ZHUANG LINGHANG (US) | 2005-01-13 | — | — | US | disclosed |
| US-20030232215-A1 | Organic Red Electro-Luminescent Device and Dopant | SYNTEC GESELLSCHAFT FUER CHEMIE UND TECHNOLOGIE DER INFORMATIONSAUFZEICHNUNG MBH (DE) | 2003-12-18 | — | — | US | disclosed |
| EP-1235467-A2 | Electroluminescent device, new luminescent compounds and doping agents | Syntec Gesellschaft für Chemie und Technologie der Informationsaufzeichnung mbH (DE) | 2002-08-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050010048-A1 | Aza-and polyaza-naphthalenly ketones useful as hiv integrase inhibitors | POLI, CYP51A1, DUT | ALDH1A1 1974/4885KMT2A 103/4885MAPT 2711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.