Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8852179 | 0.92 | OPRM1 (0.30) | OPRM1 | |
| SCHEMBL8851748 | 0.83 | — | — | |
| SCHEMBL7635943 | 0.79 | LMNA (0.33) | OPRM1EPHX1 | |
| Ammonia Solution, Strong SCHEMBL11655258 | 0.79 | DNM1 (0.38) | OPRM1TSHREPHX1 | |
| SCHEMBL159904 | 0.78 | OPRM1 (0.38) | OPRM1TSHRTHRBEPHX1 | |
| SCHEMBL2953139 | 0.77 | — | — | |
| SCHEMBL2947117 | 0.77 | — | — | |
| SCHEMBL2945891 | 0.74 | — | — | |
| SCHEMBL2952811 | 0.74 | — | — | |
| SCHEMBL8852494 | 0.74 | OPRM1 (0.32) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4958041-A | FROM TETRAALKOXYSILANE OR MONOORGANOTRIALKOXYSILANE AND GRIGNARD | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-09-18 | — | — | US | claimed |