Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 2/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10395432 | 0.86 | CYP11B2 (0.42) | CNR1KHKUSP7AXLTYRO3 | |
| SCHEMBL10395742 | 0.86 | CYP11B2 (0.46) | KHKUSP7USP30CYP11B2 | |
| SCHEMBL10396570 | 0.85 | CNR1 (0.44) | CNR1KHKAXLTYRO3CYP11B2 | |
| Hydrochloric Acid SCHEMBL10395408 | 0.84 | CNR1 (0.43) | CNR1KHKAXLTYRO3CYP11B2 | |
| SCHEMBL10395242 | 0.76 | CNR1 (0.45) | CNR1KHKUSP30CYP11B2 | |
| SCHEMBL10395270 | 0.74 | USP7 (0.44) | CNR1USP7CYP11B2 | |
| SCHEMBL9830106 | 0.74 | DRD2 (0.40) | USP30 | |
| SCHEMBL10395858 | 0.72 | CNR1 (0.52) | CNR1 | |
| SCHEMBL10396359 | 0.71 | KHK (0.54) | KHK | |
| SCHEMBL10395443 | 0.71 | KHK (0.46) | KHKCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933460-A | CHEMICAL INTERMEDIATES FOR INDAZOLE-CONTAINING DRUGS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-06-12 | — | — | US | disclosed |
| US-4853470-A | 3-(piperidinyl)- and 3-(pyrrolidinyl)-1H-indazoles | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-08-01 | — | — | US | disclosed |
| US-4806649-A | ANTIDEPRESSANTS, ANTICONVULSANTS, ANALGESICS, HYPOTENSIVE AGENTS, ANTIHALLUCINOGENS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-02-21 | — | — | US | disclosed |
| US-4775761-A | TREATING PSYCHOSES, DEPRESSION, CONVULSIONS AND HYPERTENSION | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-10-04 | — | — | US | disclosed |
| US-4758668-A | 3-(piperidinyl)- and 3-(pyrrolidinyl)-1H-indazoles | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-07-19 | — | — | US | disclosed |
| US-4710573-A | PSYCHOLOGICAL DISORDERS | HOECHST ROUSSEL PHARMACEUTICALS, INC. (US) | 1987-12-01 | — | — | US | disclosed |
| US-4670447-A | ANALGESICS, ANTIDEPRESSANTS, ANTICONVULSANTS AND HYPOTENSIVE AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-06-02 | — | — | US | disclosed |