SCHEMBL10396333

SCHEMBL10396333

O=Cc1ccc(-c2ccc(C(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.62
MEN1 O00255 2/20 0.62
MAPT P10636 2/20 0.62
KMT2A Q03164 2/20 0.62
LMNA P02545 1/20 0.62
ALDH1A1 P00352 5/20 0.57
SRD5A2 P31213 1/20 0.54
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
TRIM24 O15164 1/20 0.51
TRIM33 Q9UPN9 1/20 0.51
CYP2A6 P11509 1/20 0.50
POLB P06746 1/20 0.49
MAPK1 P28482 1/20 0.49
ATM Q13315 2/20 0.48
CDC25B P30305 1/20 0.48
TDP1 Q9NUW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18678667 0.94 ALDH1A1 (0.64) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL1047541 0.94 ALDH1A1 (0.64) RAB9AMEN1MAPTKMT2ALMNA
Benzene SCHEMBL28322201 0.94 ALDH1A1 (0.64) RAB9AMEN1MAPTKMT2ALMNA
Benzophenone SCHEMBL1074284 0.87 ALDH1A1 (0.67) RAB9AMEN1MAPTKMT2ALMNA
4-Hydroxybenzaldehyde SCHEMBL28345913 0.86 KMT2A (0.66) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL15906941 0.86 ALDH1A1 (0.54) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL6852409 0.85 ALDH1A1 (0.68) MAPTLMNAALDH1A1SRD5A2CYP2A6
SCHEMBL197633 0.85 RAB9A (0.82) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL13019488 0.85 RAB9A (0.82) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL28349357 0.85 ALDH1A1 (0.53) RAB9AMEN1KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4950809-A REACTING ARYL KETONE OR ALDEHYDE WITH PERACETIC ACID RHONE-POULENC CHIMIE (FR) 1990-08-21 US disclosed