Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3485312 | 0.92 | MTNR1A (0.42) | MTNR1AMTNR1BHSD17B2HSD17B1ALDH1A1 | |
| SCHEMBL3952524 | 0.88 | MTNR1A (0.43) | MTNR1AMTNR1BHSD17B2HSD17B1KDM4E | |
| SCHEMBL6778756 | 0.86 | MTNR1A (0.49) | MTNR1AMTNR1BHSD17B2HSD17B1KDM4E | |
| SCHEMBL28209766 | 0.85 | MTNR1A (0.49) | MTNR1AMTNR1BHSD17B2HSD17B1ALDH1A1 | |
| SCHEMBL9763801 | 0.84 | ABL1 (0.50) | MTNR1AMTNR1BKDM4EGAAL3MBTL1 | |
| SCHEMBL30501493 | 0.82 | ABL1 (0.47) | KDM4EGAAL3MBTL1LMNATDP1 | |
| SCHEMBL9581099 | 0.80 | HSD17B2 (0.50) | MTNR1AMTNR1BHSD17B2HSD17B1KMT2A | |
| SCHEMBL15038388 | 0.80 | MGLL (0.38) | L3MBTL1LMNAMAPK1HTTALDH1A1 | |
| SCHEMBL20386564 | 0.79 | CA4 (0.52) | MTNR1AMTNR1BHSD17B2HSD17B1ALDH1A1 | |
| SCHEMBL13292373 | 0.79 | BACE1 (0.38) | MAPK1HTTALDH1A1KMT2ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959288-A | Photoconductive imaging members with diaryl biarylylamine copolymer charge transport layers | XEROX CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |
| US-4946754-A | Photoconductive imaging members with diaryl biarylylamine charge transporting components | XEROX CORPORATION (US) | 1990-08-07 | — | — | US | disclosed |