Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1917212 | 0.81 | ADORA3 (0.42) | PARP1KDM4CADORA3ADORA2AADORA1 | |
| SCHEMBL9533110 | 0.81 | TDP1 (0.41) | DDAH1POLBKDM4ETNKS2PDE10A | |
| SCHEMBL2849291 | 0.80 | POLB (0.41) | PARP1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL1917495 | 0.80 | ADORA3 (0.41) | PARP1KDM4CADORA3ADORA2AADORA1 | |
| SCHEMBL20751890 | 0.80 | ADORA3 (0.41) | PARP1KDM4CADORA3ADORA2AADORA1 | |
| SCHEMBL28125053 | 0.79 | ACHE (0.39) | PARP1DDAH1POLBKDM4ETNKS2 | |
| SCHEMBL4066028 | 0.79 | KDM4E (0.40) | KDM4EPDE10ASMN1; SMN2MAPT | |
| SCHEMBL9224289 | 0.78 | KDM5B (0.50) | PARP1KDM4CADORA3ADORA2AADORA1 | |
| SCHEMBL1917518 | 0.76 | ADORA3 (0.36) | PARP1KDM4CADORA3ADORA2AADORA1 | |
| SCHEMBL10634839 | 0.75 | ACHE (0.36) | KDM4EPDE10AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929534-A | DEVELOPER RESISTANCE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-29 | — | — | US | disclosed |
| EP-0305873-A2 | Positive photosensitive composition and photosensitive registration material made therefrom | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-08 | — | — | EP | disclosed |