Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | ENO1 | P06733 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10397021 | 0.94 | MMP2 (0.34) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL10339393 | 0.88 | ENO1 (0.30) | ENO1 | |
| SCHEMBL118767 | 0.77 | GAA (0.41) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL11301792 | 0.74 | — | — | |
| SCHEMBL10396184 | 0.72 | — | — | |
| SCHEMBL10397050 | 0.67 | — | — | |
| SCHEMBL11298102 | 0.67 | MMP2 (0.39) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL3481359 | 0.67 | — | — | |
| SCHEMBL585039 | 0.65 | MMP2 (0.41) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL18261819 | 0.65 | MMP2 (0.41) | MMP2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368153-A1 | Phosphonic acid compounds and the preparation and use thereof | W.R. Grace & Co.-Conn. (US) | 1990-05-16 | — | — | EP | claimed |
| US-4911887-A | Phosphonic acid compounds and the preparation and use thereof | W. R. GRACE & CO.-CONN. (US) | 1990-03-27 | — | — | US | claimed |
| EP-0368153-A1 | Phosphonic acid compounds and the preparation and use thereof | W.R. Grace & Co.-Conn. (US) | 1990-05-16 | — | — | EP | disclosed |
| US-4911887-A | Phosphonic acid compounds and the preparation and use thereof | W. R. GRACE & CO.-CONN. (US) | 1990-03-27 | — | — | US | disclosed |