Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10397363 | 1.00 | PTPN1 (0.37) | PTPN1TSHRCYP3A4TDP1THRA | |
| SCHEMBL6041026 | 0.78 | SIRT5 (0.50) | TSHRCYP3A4THRATHRBPPARG | |
| SCHEMBL6041028 | 0.78 | SIRT5 (0.50) | TSHRCYP3A4THRATHRBPPARG | |
| Dibromotyrosine SCHEMBL838919 | 0.74 | THRB (0.58) | PTPN1CYP3A4TDP1THRATHRB | |
| Dibromotyrosine SCHEMBL145218 | 0.74 | THRB (0.58) | PTPN1CYP3A4TDP1THRATHRB | |
| SCHEMBL10397364 | 0.74 | PTPN1 (0.37) | PTPN1TSHRCYP3A4TDP1THRA | |
| Dibromotyrosine SCHEMBL145219 | 0.74 | THRB (0.58) | PTPN1CYP3A4TDP1THRATHRB | |
| Dibromotyrosine SCHEMBL29399010 | 0.73 | THRB (0.57) | CYP3A4TDP1THRATHRBPPARG | |
| SCHEMBL17559228 | 0.71 | IDO1 (0.39) | — | |
| SCHEMBL17559229 | 0.71 | IDO1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948873-A | SEX HORMONE REGULATORS | RICHTER GEDEON VEGYESZETI GYAR (HU) | 1990-08-14 | — | — | US | claimed |
| EP-0220654-A2 | Gonadoliberine analogues, process for preparing them, pharmaceutical composition and use | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1987-05-06 | — | — | EP | claimed |
| US-4948873-A | SEX HORMONE REGULATORS | RICHTER GEDEON VEGYESZETI GYAR (HU) | 1990-08-14 | — | — | US | disclosed |
| US-4948873-A | SEX HORMONE REGULATORS | RICHTER GEDEON VEGYESZETI GYAR (HU) | 1990-08-14 | — | — | US | disclosed |
| EP-0220654-A3 | GONADOLIBERINE ANALOGUES, PROCESS FOR PREPARING THEM, PHARMACEUTICAL COMPOSITION AND USE | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-09-06 | — | — | EP | disclosed |
| EP-0220654-A2 | Gonadoliberine analogues, process for preparing them, pharmaceutical composition and use | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1987-05-06 | — | — | EP | disclosed |
| EP-0220654-A2 | Gonadoliberine analogues, process for preparing them, pharmaceutical composition and use | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1987-05-06 | — | — | EP | disclosed |