Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27182697 | 0.88 | CYP1A2 (0.59) | MAPTALDH1A1CYP19A1KMT2AMEN1 | |
| SCHEMBL30873057 | 0.88 | CYP1A2 (0.59) | MAPTALDH1A1CYP19A1KMT2AMEN1 | |
| SCHEMBL28446243 | 0.87 | CA2 (0.65) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL9198420 | 0.86 | MAPT (0.69) | MAPTALDH1A1CYP19A1KMT2AMEN1 | |
| SCHEMBL9826497 | 0.85 | CYP19A1 (0.65) | MAPTALDH1A1CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL10397082 | 0.85 | CNR2 (0.56) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL70185 | 0.84 | CYP4A11 (0.75) | MAPTALDH1A1KMT2AMEN1CYP4A11 | |
| SCHEMBL10335393 | 0.82 | CYP19A1 (0.81) | MAPTALDH1A1CYP19A1KMT2ACYP1A2 | |
| Veratric Acid Methyl Ester SCHEMBL29573244 | 0.81 | MAPT (0.86) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| Veratric Acid Methyl Ester SCHEMBL2050732 | 0.81 | MAPT (0.86) | MAPTALDH1A1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4910206-A | Endotoxin induced lung injury | SANDOZ PHARMACEUTICALS CORP. (US) | 1990-03-20 | — | — | US | disclosed |