Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236957 | 0.88 | CA2 (0.61) | CA2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10397458 | 0.87 | MAPT (0.64) | CA2MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL10397103 | 0.86 | MAPT (0.61) | CA2MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL69454 | 0.84 | LOXL2 (0.70) | CA2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16573855 | 0.82 | MAPT (0.57) | CA2MAPTKMT2AMEN1CYP1A2 | |
| Veratric Acid Methyl Ester SCHEMBL29573244 | 0.81 | MAPT (0.86) | CA2MAPTKMT2AMEN1CYP1A2 | |
| Veratric Acid Methyl Ester SCHEMBL2050732 | 0.81 | MAPT (0.86) | CA2MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL2095593 | 0.80 | CA2 (1.00) | CA2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8993003 | 0.80 | CA1 (0.78) | CA2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8993024 | 0.78 | MTNR1A (0.60) | CA2MAPTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111548269-A | Preparation method of diarylmethane structure compound | 兰州大学 | 2020-08-18 | — | — | CN | disclosed |