Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.46 |
| ▸ | F13A1 | P00488 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8506280 | 0.84 | THRA (0.46) | TBXAS1MAPT | |
| SCHEMBL8503787 | 0.83 | THRA (0.42) | MAPTFFAR4 | |
| SCHEMBL19099076 | 0.80 | KDM4E (0.56) | MAPT | |
| SCHEMBL2570049 | 0.77 | TBXAS1 (0.51) | TBXAS1F13A1MAPTRXFP1CYP4A11 | |
| SCHEMBL13827596 | 0.73 | GRM5 (0.41) | — | |
| SCHEMBL17029329 | 0.73 | OPRL1 (0.41) | — | |
| SCHEMBL20818441 | 0.73 | KDM4E (0.41) | MAPT | |
| SCHEMBL22826566 | 0.72 | MAPT (0.67) | TBXAS1F13A1MAPTRXFP1LTB4R | |
| SCHEMBL26547489 | 0.71 | SHMT2 (0.51) | TBXAS1MAPTCYP4A11 | |
| SCHEMBL20817897 | 0.70 | OPRL1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |