Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | PARP1 | P09874 | 1/20 | 0.67 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.63 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.63 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.63 |
| ▸ | CASP6 | P55212 | 1/20 | 0.63 |
| ▸ | CD40 | P25942 | 2/20 | 0.59 |
| ▸ | CD40LG | P29965 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28734353 | 0.85 | NPC1 (1.00) | NPC1PARP1DUSP3PTPN5PTPN11 | |
| SCHEMBL9232842 | 0.84 | ALOX5 (0.78) | NPC1PARP1DUSP3PTPN5PTPN11 | |
| SCHEMBL11422937 | 0.83 | NPC1 (0.58) | NPC1PARP1DUSP3PTPN5PTPN11 | |
| SCHEMBL10480100 | 0.82 | NPC1 (0.72) | NPC1PARP1DUSP3PTPN5PTPN11 | |
| SCHEMBL11425944 | 0.82 | NPC1 (0.57) | NPC1PARP1DUSP3PTPN5PTPN11 | |
| SCHEMBL18992223 | 0.81 | ALOX5 (0.72) | NPC1PARP1DUSP3PTPN5PTPN11 | |
| SCHEMBL8337442 | 0.81 | NPC1 (0.80) | NPC1PARP1DUSP3PTPN5PTPN11 | |
| SCHEMBL11434698 | 0.80 | CD40 (0.66) | NPC1PARP1DUSP3PTPN5PTPN11 | |
| SCHEMBL11428711 | 0.80 | CD40 (0.66) | NPC1PARP1DUSP3PTPN5PTPN11 | |
| SCHEMBL11057910 | 0.80 | TRPV1 (0.71) | NPC1MAPTALDH1A1ALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929534-A | DEVELOPER RESISTANCE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-29 | — | — | US | disclosed |
| EP-0305873-A2 | Positive photosensitive composition and photosensitive registration material made therefrom | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-08 | — | — | EP | disclosed |
| US-3976488-A | COUPLER, EXTENDER, DISPERSION MEDIUM | MITA INDUSTRIAL COMPANY, LTD. (JA) | 1976-08-24 | — | — | US | disclosed |
| US-3948661-A | Process for diazo-type multicolor reproduction | MITA INDUSTRIAL COMPANY LTD. (JA) | 1976-04-06 | — | — | US | disclosed |
| US-3944422-A | Photosensitive material in use for diazo-type multicolor reproduction | MITA INDUSTRIAL COMPANY LIMITED (JA) | 1976-03-16 | — | — | US | disclosed |