Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.62 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.62 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | CASP6 | P55212 | 1/20 | 0.62 |
| ▸ | CD40 | P25942 | 1/20 | 0.60 |
| ▸ | CD40LG | P29965 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.54 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28734353 | 0.84 | NPC1 (1.00) | NPC1DUSP3PTPN5PTPN11KDR | |
| SCHEMBL11434114 | 0.82 | APEX1 (0.60) | NPC1DUSP3PTPN5PTPN11KDR | |
| SCHEMBL11442255 | 0.82 | APEX1 (0.60) | NPC1DUSP3PTPN5PTPN11KDR | |
| SCHEMBL10398604 | 0.82 | NPC1 (0.74) | NPC1DUSP3PTPN5PTPN11KDR | |
| SCHEMBL19021105 | 0.82 | CD40 (0.65) | NPC1DUSP3PTPN5PTPN11KDR | |
| SCHEMBL9400487 | 0.81 | NPC1 (0.63) | NPC1KDRMAPTPARP1MEN1 | |
| SCHEMBL11433131 | 0.81 | CD40 (0.69) | NPC1DUSP3PTPN5PTPN11KDR | |
| SCHEMBL9232842 | 0.81 | ALOX5 (0.78) | NPC1DUSP3PTPN5PTPN11KDR | |
| SCHEMBL8337442 | 0.80 | NPC1 (0.80) | NPC1DUSP3PTPN5PTPN11KDR | |
| SCHEMBL19021224 | 0.79 | CD40 (0.92) | NPC1DUSP3PTPN5PTPN11KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4808706-A | WET- AND LIGHFAST; SOLUBLE | CIBA-GEIGY CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |