Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399172 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL14156332 | 0.85 | MEN1 (0.60) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL14486187 | 0.83 | MTNR1A (0.39) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13515676 | 0.83 | MEN1 (0.57) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL14135780 | 0.81 | MEN1 (0.55) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL27951003 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL14156338 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL17466006 | 0.79 | MAPT (0.52) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9873850 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL14486009 | 0.79 | KDM4E (0.40) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |