SCHEMBL10399243

SCHEMBL10399243

COC(=O)c1[c]ccc(N(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.40
SMN1; SMN2 Q16637 5/20 0.40
KDM4E B2RXH2 5/20 0.40
ALDH1A1 P00352 5/20 0.40
RAB9A P51151 2/20 0.40
TSHR P16473 3/20 0.39
HPGD P15428 3/20 0.39
NPC1 O15118 3/20 0.39
HSD17B10 Q99714 3/20 0.39
MAPK1 P28482 2/20 0.39
GAA P10253 1/20 0.39
TP53 P04637 1/20 0.35
ESR2 Q92731 1/20 0.35
NOX1 Q9Y5S8 1/20 0.35
NOTUM Q6P988 1/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
KMT2A Q03164 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10399338 0.82 RAB9A (0.44) MAPTSMN1; SMN2ALDH1A1RAB9ATSHR
SCHEMBL8765661 0.80 ALDH1A1 (0.44) MAPTSMN1; SMN2KDM4EALDH1A1RAB9A
SCHEMBL11088791 0.77 TDP1 (0.44) MAPTSMN1; SMN2KDM4EALDH1A1TSHR
SCHEMBL28294101 0.77 NR4A2 (0.41) MAPTSMN1; SMN2KDM4EALDH1A1RAB9A
SCHEMBL128693 0.77 CA1 (0.48) MAPTSMN1; SMN2KDM4EALDH1A1RAB9A
SCHEMBL11086126 0.77 CA12 (0.47) MAPTSMN1; SMN2KDM4EALDH1A1TSHR
SCHEMBL3982238 0.75 MEN1 (0.42) MAPTSMN1; SMN2KDM4EALDH1A1RAB9A
SCHEMBL1867402 0.75 ABL1 (0.46) MAPTSMN1; SMN2KDM4EALDH1A1RAB9A
SCHEMBL11085145 0.75 GAA (0.47) MAPTSMN1; SMN2KDM4EALDH1A1RAB9A
SCHEMBL1637879 0.75 CA1 (0.46) MAPTSMN1; SMN2KDM4EALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4966983-A PRESSURE OR HEAT SENSITIVE ELEMENTS BASF AKTIENGESELLSCHAFT (DE) 1990-10-30 US disclosed
US-4841050-A Carbazole containing benzopyrans BASF AKTIENGESELLSCHAFT (DE) 1989-06-20 US disclosed
EP-0236973-B1 BENZOPYRANES AND THEIR USE IN A RECORDING SYSTEM BASF Aktiengesellschaft (DE) 1989-06-14 EP disclosed