SCHEMBL1867402

SCHEMBL1867402

COC(=O)c1[c]ccc(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.46
NR4A2 P43354 2/20 0.41
MAPT P10636 5/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
KDM4E B2RXH2 2/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
MEN1 O00255 2/20 0.38
HTT P42858 2/20 0.38
KMT2A Q03164 2/20 0.38
XBP1 P17861 1/20 0.38
SLC6A3 Q01959 5/20 0.38
ATM Q13315 1/20 0.38
LMNA P02545 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ALPL P05186 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28887661 0.82 SLC6A3 (0.45) ABL1MAPTALDH1A1SMN1; SMN2NPC1
SCHEMBL1299593 0.81 CNR1 (0.40) ABL1SMN1; SMN2MEN1KMT2ALMNA
SCHEMBL11839343 0.81 ALOX15 (0.46) MAPTALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL128693 0.79 CA1 (0.48) MAPTALDH1A1HPGDSMN1; SMN2RAB9A
SCHEMBL28294101 0.79 NR4A2 (0.41) NR4A2MAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL11086126 0.79 CA12 (0.47) MAPTALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL11088791 0.79 TDP1 (0.44) NR4A2MAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL7574859 0.79 FSCN1 (0.35) MAPTALDH1A1HPGDSMN1; SMN2NPC1
SCHEMBL11085145 0.78 GAA (0.47) ABL1MAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL3982238 0.78 MEN1 (0.42) MAPTALDH1A1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071506-B Substituted 2- (hetero) arylimidazolyl carboxamides as pest control agents 拜耳作物科学股份公司 2021-03-02 CN claimed
US-10544124-B2 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-01-28 US claimed
US-20190047982-A1 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-02-14 US claimed
EP-3414236-A1 SUBSTITUIERTED 2-(HET)ARYL-IMIDAZOLYL-CARBOXYAMIDES AS PEST CONTROL AGENTS Bayer CropScience Aktiengesellschaft (DE) 2018-12-19 EP claimed
WO-2017137338-A1 SUBSTITUIERTED 2-(HET)ARYL-IMIDAZOLYL-CARBOXYAMIDES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-08-17 WO claimed
EP-0031708-B1 CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR ICI PHARMA (FR) 1984-06-13 EP claimed
EP-0031708-A2 Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor ICI PHARMA (FR) 1981-07-08 EP claimed
US-4085099-A AZO DYES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-04-18 US claimed
CN-113321659-B Organic electroluminescent material and device thereof 武汉尚赛光电科技有限公司 2023-04-18 CN disclosed
US-20220192185-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HIGHLY SULFONATED LIGNOSULFONATE BASF SE (DE) 2022-06-23 US disclosed
US-20220183278-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HYDROPHOBIC FUMED SILICA BASF SE (DE) 2022-06-16 US disclosed
US-20220159957-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN BASF SE (DE) 2022-05-26 US disclosed
EP-3962269-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN BASF SE (DE) 2022-03-09 EP disclosed
CN-113795148-A Stabilization of suspension concentrates by highly sulfonated lignosulfonates 巴斯夫欧洲公司 2021-12-14 CN disclosed
EP-1691777-A2 NOVEL DIFFERENTIAL IMAGING METHOD Medi-Physics, Inc. (US) 2006-08-23 EP disclosed
WO-2005053615-A9 NOVEL DIFFERENTIAL IMAGING METHOD MEDI PHYSICS INC (US) 2005-09-01 WO disclosed
WO-2005053615-A2 NOVEL DIFFERENTIAL IMAGING METHOD MEDI-PHYSICS, INC. (US) 2005-06-16 WO disclosed
US-4463173-A ANTIBIOTIC, BACTERICIDE ICI PHARMA (FR) 1984-07-31 US disclosed
EP-0031708-B1 CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR ICI PHARMA (FR) 1984-06-13 EP disclosed
EP-0031708-A2 Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor ICI PHARMA (FR) 1981-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190047982-A1 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides DDT, CYP4X1, CYP4Z1 ABL1 585/4885NR4A2 1739/4885MAPT 4737/4885
US-20220159957-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN ERO1A, ERLIN2, ERLIN1 ABL1 1716/4885NR4A2 3528/4885MAPT 1368/4885
US-20220192185-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HIGHLY SULFONATED LIGNOSULFONATE LSS, STS, U2SURP ABL1 2971/4885NR4A2 4491/4885MAPT 1851/4885
US-20220183278-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HYDROPHOBIC FUMED SILICA RCC1, SAMM50, PIGS ABL1 3247/4885NR4A2 4403/4885MAPT 695/4885
US-10544124-B2 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides DDT, CYP4X1, CYP4Z1 ABL1 585/4885NR4A2 1739/4885MAPT 4737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.