Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28946280 | 0.86 | SIGMAR1 (0.45) | HPGDKMT2A | |
| SCHEMBL10399284 | 0.86 | HPGD (0.48) | HPGDNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL28799060 | 0.84 | HPGD (0.51) | HPGDNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL28799044 | 0.83 | KDM1A (0.42) | HPGDKMT2AALDH1A1TP53 | |
| SCHEMBL28799042 | 0.82 | KDM1A (0.42) | HPGDALDH1A1 | |
| SCHEMBL4163752 | 0.80 | SMN1; SMN2 (0.47) | HPGDPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL4160380 | 0.80 | HSP90AA1 (0.46) | HPGDRAB9AALDH1A1 | |
| SCHEMBL4154957 | 0.79 | SMN1; SMN2 (0.46) | HPGDPOLBNPC1RAB9AKMT2A | |
| SCHEMBL10388494 | 0.79 | HPGD (0.51) | HPGDPOLBNPC1RAB9AKMT2A | |
| SCHEMBL10388311 | 0.79 | NPC1 (0.47) | HPGDNPC1RAB9AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4966983-A | PRESSURE OR HEAT SENSITIVE ELEMENTS | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-30 | — | — | US | disclosed |
| US-4841050-A | Carbazole containing benzopyrans | BASF AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| EP-0236973-B1 | BENZOPYRANES AND THEIR USE IN A RECORDING SYSTEM | BASF Aktiengesellschaft (DE) | 1989-06-14 | — | — | EP | disclosed |
| EP-0236973-A2 | Benzopyranes and their use in a recording system | BASF Aktiengesellschaft (DE) | 1987-09-16 | — | — | EP | disclosed |