Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399266 | 0.86 | HPGD (0.51) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28946280 | 0.82 | SIGMAR1 (0.45) | HPGDKMT2A | |
| SCHEMBL4157341 | 0.82 | MAPT (0.47) | HPGDRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL28799060 | 0.81 | HPGD (0.51) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28799044 | 0.79 | KDM1A (0.42) | HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL971067 | 0.76 | HPGD (0.51) | HPGDHTTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4160380 | 0.76 | HSP90AA1 (0.46) | HPGDHTTCYP2C9CYP2C19RAB9A | |
| SCHEMBL28799050 | 0.74 | KDM1A (0.44) | — | |
| SCHEMBL28799042 | 0.72 | KDM1A (0.42) | HPGDALDH1A1 | |
| SCHEMBL11960910 | 0.72 | RAB9A (0.58) | HPGDHTTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4966983-A | PRESSURE OR HEAT SENSITIVE ELEMENTS | BASF AKTIENGESELLSCHAFT (DE) | 1990-10-30 | — | — | US | disclosed |
| US-4841050-A | Carbazole containing benzopyrans | BASF AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| EP-0236973-B1 | BENZOPYRANES AND THEIR USE IN A RECORDING SYSTEM | BASF Aktiengesellschaft (DE) | 1989-06-14 | — | — | EP | disclosed |