Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 15/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.46 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399266 | 0.80 | HPGD (0.51) | ALDH1A1HPGDRAB9A | |
| SCHEMBL28946280 | 0.76 | SIGMAR1 (0.45) | HSP90AA1HPGD | |
| SCHEMBL10399284 | 0.76 | HPGD (0.48) | ALDH1A1CYP2C9HPGDCYP2C19HTT | |
| SCHEMBL28799060 | 0.75 | HPGD (0.51) | ALDH1A1HPGDRAB9A | |
| SCHEMBL28799044 | 0.74 | KDM1A (0.42) | ALDH1A1HPGD | |
| SCHEMBL12569373 | 0.73 | HPGD (0.64) | HSP90AA1HSP90AB1HSP90B1TRAP1NAMPT | |
| SCHEMBL4156420 | 0.72 | HDAC1 (0.44) | HSP90AA1HSP90AB1HSP90B1TRAP1NAMPT | |
| SCHEMBL28799050 | 0.71 | KDM1A (0.44) | — | |
| SCHEMBL4145940 | 0.71 | HSP90AA1 (0.72) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL4163325 | 0.71 | TRAP1 (0.70) | HSP90AA1HSP90AB1HSP90B1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | HSP90AB1, HSP90AA1, HSP90AB2P | HSP90AA1 2/4885HSP90AB1 1/4885HSP90B1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.