Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.49 |
| ▸ | HRH2 | P25021 | 8/20 | 0.49 |
| ▸ | HRH1 | P35367 | 8/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399310 | 0.94 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EHTTL3MBTL1 | |
| SCHEMBL16437760 | 0.90 | HRH3 (0.50) | ALDH1A1HPGDKDM4EHTTL3MBTL1 | |
| SCHEMBL8939343 | 0.87 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EHTTL3MBTL1 | |
| SCHEMBL12736277 | 0.87 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EHTTL3MBTL1 | |
| SCHEMBL10399387 | 0.87 | HRH3 (0.48) | ALDH1A1HPGDHRH3HRH2HRH1 | |
| SCHEMBL10594224 | 0.87 | HRH3 (0.48) | ALDH1A1HPGDHRH3HRH2HRH1 | |
| SCHEMBL16437761 | 0.85 | MMP3 (0.50) | ALDH1A1HPGDKDM4EHTTL3MBTL1 | |
| SCHEMBL21156855 | 0.84 | MMP2 (0.54) | ALDH1A1HPGDHRH3HRH2HRH1 | |
| SCHEMBL25192787 | 0.84 | KDM4E (0.68) | ALDH1A1HPGDKDM4EHTTL3MBTL1 | |
| SCHEMBL503737 | 0.84 | KDM4E (0.68) | ALDH1A1HPGDKDM4EHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956488-A | Optically active cyanobiphenyl compound | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | claimed |
| US-4956488-A | Optically active cyanobiphenyl compound | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |