SCHEMBL10399359

SCHEMBL10399359

C=CCNCc1ccc(CC)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.46
ALDH1A1 P00352 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
POLB P06746 2/20 0.40
APAF1 O14727 1/20 0.40
USP2 O75604 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40
MAPK1 P28482 1/20 0.40
CASP1 P29466 1/20 0.40
BLM P54132 1/20 0.40
HSD17B10 Q99714 1/20 0.40
DPP7 Q9UHL4 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17291833 0.89 DPP7 (0.44) LMNAALDH1A1MEN1KMT2ADPP7
SCHEMBL19700185 0.83 CHRM2 (0.52) LMNAL3MBTL1ALDH1A1NPSR1MEN1
Hydrochloric Acid SCHEMBL28115031 0.82 CHRM2 (0.50) LMNAL3MBTL1ALDH1A1NPSR1MEN1
SCHEMBL28674603 0.80 POLB (0.51) LMNAL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL4396092 0.79 LMNA (0.77) LMNAL3MBTL1ALDH1A1NPSR1MEN1
SCHEMBL23997398 0.79 PYCR1 (0.50) LMNAPOLBDPP7SMN1; SMN2
SCHEMBL11567636 0.79 ALDH1A1 (0.46) LMNAALDH1A1MEN1KMT2AMAPT
SCHEMBL6560123 0.79 CHRM2 (0.52) L3MBTL1ALDH1A1MEN1KMT2AGAA
Ethylbenzene SCHEMBL11526245 0.79 TP53 (0.58) L3MBTL1ALDH1A1NPSR1MEN1KMT2A
SCHEMBL8018076 0.79 CA1 (0.44) L3MBTL1ALDH1A1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4892918-A TOUGHENING THERMOSETTING MATRIX RESINS BASF CORPORATION (US) 1990-01-09 US disclosed
US-4847154-A Thermosetting resin systems containing secondary amine-terminated siloxane modifiers BASF CORPORATION (US) 1989-07-11 US disclosed