Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.59 |
| ▸ | PGK1 | P00558 | 1/20 | 0.58 |
| ▸ | PGK2 | P07205 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10399464 | 0.99 | ADORA2A (0.63) | ADORA2AADORA3ADORA2BADORA1LMNA | |
| SCHEMBL10399499 | 0.91 | ADORA2A (0.63) | ADORA2AADORA2BLMNAMAPTNPSR1 | |
| SCHEMBL10399798 | 0.91 | PGK1 (0.70) | ADORA2AADORA3ADORA2BADORA1TSHR | |
| SCHEMBL10398375 | 0.89 | ADORA2A (0.66) | ADORA2AADORA2BLMNAMAPTNPSR1 | |
| SCHEMBL10399501 | 0.89 | ADORA2A (0.76) | ADORA2AADORA3ADORA2BADORA1LMNA | |
| SCHEMBL10399357 | 0.86 | ADORA2A (0.68) | ADORA2AADORA3ADORA2BADORA1SLC29A1 | |
| SCHEMBL10398379 | 0.83 | SLC29A1 (0.60) | ADORA2AADORA3ADORA2BADORA1SLC29A1 | |
| SCHEMBL27881271 | 0.81 | TSHR (0.83) | ADORA2AADORA3ADORA1LMNAMAPT | |
| SCHEMBL10338503 | 0.79 | ADORA2A (0.75) | ADORA2AADORA3ADORA2B | |
| SCHEMBL10588074 | 0.78 | ADORA2A (0.82) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977144-A | ADENOSINE AGONISTS | CIBA-GEIGY CORPORATION (US) | 1990-12-11 | — | — | US | claimed |