Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.76 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.58 |
| ▸ | PGK1 | P00558 | 3/20 | 0.58 |
| ▸ | PGK2 | P07205 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399798 | 0.90 | PGK1 (0.70) | ADORA2AADORA2BADORA3ADORA1PGK1 | |
| SCHEMBL10399504 | 0.89 | ADORA2A (0.64) | ADORA2AADORA2BADORA3ADORA1PGK1 | |
| SCHEMBL10399499 | 0.89 | ADORA2A (0.63) | ADORA2AADORA2BPGK1PGK2LMNA | |
| Hydrochloric Acid SCHEMBL10399464 | 0.88 | ADORA2A (0.63) | ADORA2AADORA2BADORA3ADORA1PGK1 | |
| SCHEMBL10399463 | 0.86 | ADORA2A (0.58) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL9762945 | 0.86 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1TSHR | |
| SCHEMBL10588368 | 0.86 | ADORA2A (1.00) | ADORA2AADORA2BADORA3ADORA1TSHR | |
| SCHEMBL10398375 | 0.86 | ADORA2A (0.66) | ADORA2AADORA2BLMNAMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL9762842 | 0.86 | ADORA2A (0.98) | ADORA2AADORA2BADORA3ADORA1TSHR | |
| SCHEMBL10399357 | 0.85 | ADORA2A (0.68) | ADORA2AADORA2BADORA3ADORA1PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977144-A | ADENOSINE AGONISTS | CIBA-GEIGY CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0354180-A2 | Certain imidazo[4,5-b]pyridine derivatives | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |