SCHEMBL10399528

SCHEMBL10399528

C=C(Cl)C(=O)N(CCC)CCC

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.44
CA9 Q16790 4/20 0.44
CA2 P00918 3/20 0.44
TSHR P16473 2/20 0.41
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 2/20 0.39
HPGD P15428 1/20 0.39
TP53 P04637 2/20 0.38
CA1 P00915 3/20 0.37
EGFR P00533 1/20 0.33
ERBB2 P04626 1/20 0.33
BCHE P06276 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
MLYCD O95822 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10399511 0.80 ALDH1A1 (0.39) CA12CA9CA2TSHRALDH1A1
SCHEMBL154162 0.78 CA12 (0.46) CA12CA9CA2TSHRMAPK1
SCHEMBL11521817 0.76 TSHR (0.46) CA12CA9CA2TSHRMAPK1
SCHEMBL1628759 0.74 CA12 (0.43) CA12CA9CA2TSHRMAPK1
SCHEMBL856638 0.74 CA12 (0.52) CA12CA9CA2TSHRMAPK1
SCHEMBL3900327 0.73 CA12 (0.41) CA12CA9CA2TSHRMAPK1
SCHEMBL4978433 0.73 CA12 (0.41) CA12CA9CA2TSHRMAPK1
SCHEMBL10445563 0.72 CA12 (0.50) CA12CA9CA2TSHRMAPK1
SCHEMBL583897 0.72 CA12 (0.50) CA12CA9CA2TSHRMAPK1
SCHEMBL1629289 0.71 CES1 (0.41) CA12CA9CA2TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4935527-A SEPARATION FROM IMPURITIES BY ION EXCHANGING ON A CATIONIC EXCHANGER BED RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) 1990-06-19 US disclosed
EP-0191462-A1 Purification of aziridine-2-carboxylic acid salts RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) 1986-08-20 EP disclosed