Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653040 | 0.99 | PTGS2 (0.47) | PTGS2PTGS1MAPTNPC1RAB9A | |
| SCHEMBL9653034 | 0.99 | PTGS2 (0.47) | PTGS2PTGS1MAPTNPC1RAB9A | |
| SCHEMBL8422918 | 0.90 | PTGS2 (0.51) | PTGS2PTGS1MAPTNPC1RAB9A | |
| SCHEMBL8645474 | 0.90 | PTGS2 (0.51) | PTGS2PTGS1MAPTNPC1RAB9A | |
| SCHEMBL9362316 | 0.86 | MAPT (0.56) | PTGS2PTGS1MAPTNPC1RAB9A | |
| SCHEMBL9362320 | 0.86 | MAPT (0.56) | PTGS2PTGS1MAPTNPC1RAB9A | |
| SCHEMBL592174 | 0.84 | MAPT (0.55) | PTGS2PTGS1MAPTNPC1RAB9A | |
| SCHEMBL592173 | 0.84 | MAPT (0.55) | PTGS2PTGS1MAPTNPC1RAB9A | |
| SCHEMBL9358492 | 0.84 | MAPT (0.55) | PTGS2PTGS1MAPTNPC1RAB9A | |
| SCHEMBL9358488 | 0.84 | MAPT (0.55) | PTGS2PTGS1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963633-A | Bisacrylate monomers and polymers exhibiting nonlinear optical response | HOECHST CELANESE CORP. (US) | 1990-10-16 | — | — | US | disclosed |
| US-4929696-A | Bisacrylate monomers and polymers exhibiting nonlinear optical response | HOECHST CELANESE CORP. (US) | 1990-05-29 | — | — | US | disclosed |
| US-4922003-A | Bisacrylate monomers and polymers exhibiting nonlinear optical response | HOECHST CELANESE CORP. (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0321891-A2 | Bisacrylate monomers and polymers exhibiting nonlinear optical response | HOECHST CELANESE CORPORATION (US) | 1989-06-28 | — | — | EP | disclosed |