Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.33 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10520209 | 0.85 | PKM (0.45) | PKMALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL10400917 | 0.83 | PKM (0.42) | PKMALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL10400903 | 0.81 | ALDH1A1 (0.37) | PKMALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL10389921 | 0.81 | ALDH1A1 (0.37) | PKMALDH1A1LMNASMN1; SMN2CYP3A4 | |
| Isopropylamine SCHEMBL10733802 | 0.81 | PKM (0.36) | PKMALDH1A1LMNASMN1; SMN2CYP3A4 | |
| Isopropylamine SCHEMBL10520663 | 0.80 | PKM (0.41) | PKMALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL10672192 | 0.80 | ALDH1A1 (0.43) | PKMALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL10477941 | 0.79 | PKM (0.34) | PKMALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL10566340 | 0.78 | PKM (0.33) | PKMALDH1A1LMNASMN1; SMN2AR | |
| SCHEMBL10401080 | 0.77 | OXTR (0.40) | CCR2TSHRNR3C1ARKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4936892-A | HERBICIDES; PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-26 | — | — | US | disclosed |
| EP-0302328-A2 | 1-Aryl pyrazoles | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |