Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400917 | 0.84 | PKM (0.42) | PKMSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL10478125 | 0.84 | TDP1 (0.35) | PKMSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL10478129 | 0.84 | TDP1 (0.35) | PKMSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL10731575 | 0.83 | PKM (0.41) | PKMSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL10522944 | 0.82 | GABRB3 (0.41) | PKMALDH1A1TDP1CYP3A4HPGD | |
| SCHEMBL10627213 | 0.82 | GABRB3 (0.40) | PKMSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL10627175 | 0.81 | TDP1 (0.39) | PKMSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL10371785 | 0.81 | MAPT (0.39) | PKMSMN1; SMN2ALDH1A1TDP1CYP3A4 | |
| SCHEMBL10388804 | 0.79 | CYP3A4 (0.43) | SMN1; SMN2ALDH1A1TDP1CYP3A4HPGD | |
| SCHEMBL10560650 | 0.79 | MAPK1 (0.40) | PKMSMN1; SMN2ALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4936892-A | HERBICIDES; PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-26 | — | — | US | disclosed |
| EP-0302328-A2 | 1-Aryl pyrazoles | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |