Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10478125 | 1.00 | TDP1 (0.35) | TDP1MAPTPKMSMN1; SMN2GABRP | |
| SCHEMBL10477776 | 0.95 | GABRP (0.38) | TDP1MAPTPKMSMN1; SMN2GABRP | |
| SCHEMBL10477777 | 0.95 | GABRP (0.38) | TDP1MAPTPKMSMN1; SMN2GABRP | |
| SCHEMBL10477941 | 0.85 | PKM (0.34) | MAPTPKMSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10400400 | 0.84 | PKM (0.40) | TDP1MAPTPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL10477782 | 0.82 | ALDH1A1 (0.36) | TDP1MAPTPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL10400917 | 0.78 | PKM (0.42) | TDP1MAPTPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL10560650 | 0.77 | MAPK1 (0.40) | TDP1MAPTPKMSMN1; SMN2GABRP | |
| SCHEMBL10522944 | 0.76 | GABRB3 (0.41) | TDP1PKMGABRPGABRDGABRA1 | |
| SCHEMBL10549778 | 0.75 | MAPK1 (0.41) | TDP1MAPTPKMSMN1; SMN2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4799951-A | 5-acylamino-pyrazole derivatives, composition containing them and herbicidal method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-24 | — | — | US | claimed |