SCHEMBL10400960

SCHEMBL10400960

CC1=C(C)CC2C(=O)NC(=O)C2C1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.36
TSHR P16473 1/20 0.33
PARP1 P09874 1/20 0.33
MAP3K14 Q99558 1/20 0.33
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10632824 0.73 TSHR (0.36) TSHRALDH1A1MAPTPKMHPGD
SCHEMBL2984006 0.72 MAP3K14 (0.33) CRBNMAP3K14
SCHEMBL7307825 0.72 MAP3K14 (0.33) CRBNMAP3K14
SCHEMBL9502227 0.72 TSHR (0.39) TSHRALDH1A1PKMHPGD
SCHEMBL5909391 0.71 MAP3K14 (0.55) CRBNTSHRMAP3K14MAPTPKM
SCHEMBL18545242 0.69 MAP3K14 (0.33) CRBNMAP3K14
SCHEMBL455753 0.69
SCHEMBL3628793 0.69 MAP3K14 (0.33) CRBNMAP3K14
SCHEMBL9263356 0.69 GAA (0.31) CRBNTSHR
SCHEMBL1629009 0.69 TSHR (0.34) TSHRALDH1A1MAPTPKMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399351-A2 Epoxy resin and water borne coatings therefrom THE DOW CHEMICAL COMPANY (US) 1990-11-28 EP disclosed
US-4946911-A CONTAINING UNSATURATED IMIDE THE DOW CHEMICAL COMPANY (US) 1990-08-07 US disclosed