Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.40 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824999 | 0.88 | ALDH1A1 (0.48) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL19896370 | 0.83 | ALDH1A1 (0.46) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL5026819 | 0.81 | ALDH1A1 (0.50) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL5026818 | 0.81 | ALDH1A1 (0.50) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL112254 | 0.81 | ALDH1A1 (0.50) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL3244031 | 0.78 | ALDH1A1 (0.57) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| Acetic Acid SCHEMBL21408590 | 0.78 | ALDH1A1 (0.47) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL3244027 | 0.78 | ALDH1A1 (0.57) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL3244029 | 0.78 | ALDH1A1 (0.57) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL31053838 | 0.78 | ALDH1A1 (0.57) | ALOX15ALDH1A1CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3217212-A1 | LIQUID CRYSTAL DISPLAY ELEMENT | Nissan Chemical Industries, Ltd. (JP) | 2017-09-13 | — | — | EP | disclosed |
| US-8357723-B2 | Prodrugs containing novel bio-cleavable linkers | Piramal Enterprises Limited and Apparao Satyam (IN) | 2013-01-22 | — | — | US | disclosed |
| US-8354455-B2 | Prodrugs containing novel bio-cleavable linkers | Piramal Enterprises Limited and Apparao Satyam (IN) | 2013-01-15 | — | — | US | disclosed |
| US-8349901-B2 | Prodrugs containing novel bio-cleavable linkers | Piramal Enterprises Limited and Apparao Satyam (IN) | 2013-01-08 | — | — | US | disclosed |
| US-8299176-B2 | Thermosetting poly(thio)urethane formulation comprising at least one block copolymer and use thereof in optics for the production of organic lenses having improved toughness | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2012-10-30 | — | — | US | disclosed |
| US-20110274695-A1 | PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS | PIRAMAL LIFE SCIENCES LIMITED | 2011-11-10 | — | — | US | disclosed |
| US-20110269709-A1 | PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS | PIRAMAL LIFE SCIENCES LIMITED | 2011-11-03 | — | — | US | disclosed |
| US-20110269722-A1 | PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS | Piramal Life Science Limited | 2011-11-03 | — | — | US | disclosed |
| US-7932294-B2 | Prodrugs containing novel bio-cleavable linkers | APPARAO SATYAM (IN) | 2011-04-26 | — | — | US | disclosed |
| EP-2269657-A2 | Prodrugs containing novel bio-cleavable linkers | Piramal Life Sciences Limited (IN) | 2011-01-05 | — | — | EP | disclosed |
| US-20060046967-A1 | Prodrugs containing novel bio-cleavable linkers | Piramal Enterprises Limited (IN) | 2006-03-02 | — | — | US | disclosed |
| US-6635730-B1 | Photopolymerizable composition forming lenses with low yellowing index and good resistance to aging | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2003-10-21 | — | — | US | disclosed |
| US-6627718-B2 | Polythio(meth)acrylate, bridged ethylenically unsaturated monomoer, and polythiol | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2003-09-30 | — | — | US | disclosed |
| US-20030109655-A1 | Polymerizable compositions for making optical lens with high refractive index and high abbe number, and resulting lens | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2003-06-12 | — | — | US | disclosed |
| US-6533815-B1 | Polythioether-copolycarbon/other/ copolymer; copolymer of a polythiol monomer and a bis-norbornene monomer | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2003-03-18 | — | — | US | disclosed |
| US-6479606-B1 | Polymerizable compositions for making optical lens with high refractive index and high abbe number, and resulting lens | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2002-11-12 | — | — | US | disclosed |
| EP-0394495-B1 | 4,4'-BIS(METHACRYLOYLTHIO)DIPHENYL SULFIDE AND CURABLE COMPOSITION CONTAINING SAME | SUMITOMO SEIKA CHEMICALS (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5270439-A | Method of producing a curable composition containing 4,4'-bis(methacryloylthio)diphenylsulfide | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| US-5183917-A | Curable; optics, coatings, seals, adhesives, paints | SHOWA DENKO K.K. (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0394495-A1 | 4,4'-BIS(METHACRYLOYLTHIO)DIPHENYL SULFIDE AND CURABLE COMPOSITION CONTAINING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269722-A1 | PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS | SI, UGT1A1, CYP2B6 | ALOX15 1077/4885ALDH1A1 229/4885CHRM5 3791/4885 |
| US-20110274695-A1 | PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS | SI, UGT1A1, CYP2B6 | ALOX15 1077/4885ALDH1A1 229/4885CHRM5 3791/4885 |
| US-20060046967-A1 | Prodrugs containing novel bio-cleavable linkers | SI, UGT1A1, CYP2B6 | ALOX15 1077/4885ALDH1A1 229/4885CHRM5 3791/4885 |
| US-20110269709-A1 | PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS | SI, UGT1A1, CYP2B6 | ALOX15 1077/4885ALDH1A1 229/4885CHRM5 3791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.