Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244029 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRCA2CA1ALOX15 | |
| SCHEMBL31053838 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRCA2CA1ALOX15 | |
| SCHEMBL3244031 | 1.00 | ALDH1A1 (0.57) | ALDH1A1TSHRCA2CA1ALOX15 | |
| SCHEMBL19896423 | 0.94 | ALDH1A1 (0.55) | ALDH1A1TSHRCA1ALOX15LMNA | |
| SCHEMBL28425931 | 0.93 | ALDH1A1 (0.53) | ALDH1A1TSHRFAAH | |
| SCHEMBL19896365 | 0.93 | ALDH1A1 (0.53) | ALDH1A1TSHRFAAH | |
| SCHEMBL112254 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15LMNAHSD17B10 | |
| SCHEMBL5026818 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15LMNAHSD17B10 | |
| SCHEMBL5026819 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15LMNAHSD17B10 | |
| Methane SCHEMBL28237192 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRALOX15LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130295229-A1 | THIOLS AS FLAVORING INGREDIENT | FIRMENICH SA (CH) | 2013-11-07 | — | — | US | claimed |
| US-20100303988-A1 | THIOLS AS FLAVORING INGREDIENT | FIRMENICH SA | 2010-12-02 | — | — | US | claimed |
| EP-1882027-B1 | THIOLS AS FLAVORING INGREDIENT | FIRMENICH & CIE (CH) | 2010-07-21 | — | — | EP | claimed |
| US-10993464-B2 | Thiols as flavoring ingredient | FIRMENICH SA (CH) | 2021-05-04 | — | — | US | disclosed |
| US-20180055077-A1 | THIOLS AS FLAVORING INGREDIENT | FIRMENICH SA (CH) | 2018-03-01 | — | — | US | disclosed |
| US-20130295229-A1 | THIOLS AS FLAVORING INGREDIENT | FIRMENICH SA (CH) | 2013-11-07 | — | — | US | disclosed |
| US-20100303988-A1 | THIOLS AS FLAVORING INGREDIENT | FIRMENICH SA | 2010-12-02 | — | — | US | disclosed |
| EP-1882027-B1 | THIOLS AS FLAVORING INGREDIENT | FIRMENICH & CIE (CH) | 2010-07-21 | — | — | EP | disclosed |
| EP-1882027-A1 | THIOLS AS FLAVORING INGREDIENT | FIRMENICH SA (CH) | 2008-01-30 | — | — | EP | disclosed |
| US-20080020116-A1 | THIOLS AS FLAVORING INGREDIENT | FIRMENICH SA (CH) | 2008-01-24 | — | — | US | disclosed |
| WO-2006120625-A1 | THIOLS AS FLAVORING INGREDIENT | FIRMENICH SA (CH) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10993464-B2 | Thiols as flavoring ingredient | TAS1R3, TMT1A, TST | ALDH1A1 213/4885TSHR 2728/4885CA2 3347/4885 |
| US-20180055077-A1 | THIOLS AS FLAVORING INGREDIENT | TAS1R3, TMT1A, TST | ALDH1A1 213/4885TSHR 2728/4885CA2 3347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.