Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401849 | 0.86 | CHRM4 (0.54) | SMN1; SMN2HTTMEN1KMT2ALMNA | |
| SCHEMBL10401770 | 0.85 | CHRM4 (0.57) | SMN1; SMN2HTTMEN1KMT2ALMNA | |
| SCHEMBL10401922 | 0.82 | MAPT (0.51) | SMN1; SMN2HTTMEN1KMT2ALMNA | |
| SCHEMBL10401434 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2HTTMEN1KMT2ALMNA | |
| SCHEMBL10401523 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2LMNAMAPTTP53CYP1A2 | |
| SCHEMBL10401582 | 0.81 | TP53 (0.60) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL3043309 | 0.81 | GFER (0.55) | SMN1; SMN2KMT2ALMNAMAPTTP53 | |
| SCHEMBL10401512 | 0.81 | GFER (0.58) | SMN1; SMN2HTTMEN1KMT2ALMNA | |
| SCHEMBL10401826 | 0.81 | DRD2 (0.62) | SMN1; SMN2HTTMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL10402024 | 0.80 | GFER (0.57) | SMN1; SMN2HTTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960776-A | ANTIALLERGENS | A. H. ROBINS COMPANY, INC. (US) | 1990-10-02 | — | — | US | claimed |
| EP-0277725-A2 | 4-Aryl-N-[2-(dialkylamino and heterocyclicamino) alkyl]-1-piperazinecarboxamides and their use as anti allergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-08-10 | — | — | EP | claimed |
| US-4960776-A | ANTIALLERGENS | A. H. ROBINS COMPANY, INC. (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0277725-A2 | 4-Aryl-N-[2-(dialkylamino and heterocyclicamino) alkyl]-1-piperazinecarboxamides and their use as anti allergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-08-10 | — | — | EP | disclosed |