Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | APAF1 | O14727 | 1/20 | 0.62 |
| ▸ | MITF | O75030 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Elliptinone SCHEMBL29929970 | 0.83 | MAPT (0.62) | MAPTALDH1A1LMNAAPAF1MITF | |
| SCHEMBL3427985 | 0.82 | ALDH1A1 (0.64) | MAPTALDH1A1LMNAAPAF1MITF | |
| SCHEMBL1701095 | 0.80 | MAPT (0.64) | MAPTALDH1A1LMNAAPAF1MITF | |
| SCHEMBL29601012 | 0.80 | MAPT (0.64) | MAPTALDH1A1LMNAAPAF1MITF | |
| SCHEMBL19449185 | 0.80 | MAPT (0.59) | MAPTALDH1A1LMNAAPAF1MITF | |
| SCHEMBL9627716 | 0.77 | ALDH1A1 (1.00) | MAPTALDH1A1LMNAAPAF1MITF | |
| SCHEMBL30003269 | 0.77 | ALDH1A1 (1.00) | MAPTALDH1A1LMNAAPAF1MITF | |
| SCHEMBL23271796 | 0.75 | MAPT (0.64) | MAPTALDH1A1LMNAAPAF1MITF | |
| SCHEMBL30003449 | 0.75 | MAPT (0.64) | MAPTALDH1A1LMNAAPAF1MITF | |
| SCHEMBL1426486 | 0.73 | MAPT (1.00) | MAPTALDH1A1MITFMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4895575-A | HAIR DYES | L'OREAL (FR) | 1990-01-23 | — | — | US | claimed |
| US-4895575-A | HAIR DYES | L'OREAL (FR) | 1990-01-23 | — | — | US | disclosed |