SCHEMBL3427985

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10401558	0.82	MAPT (0.62)	ALDH1A1MAPTLMNAAPAF1MITF
	SCHEMBL12253692	0.80	RAB9A (0.76)	ALDH1A1MAPTLMNAHTTRAB9A
	SCHEMBL30003269	0.78	ALDH1A1 (1.00)	ALDH1A1MAPTLMNAAPAF1MITF
	SCHEMBL9627716	0.78	ALDH1A1 (1.00)	ALDH1A1MAPTLMNAAPAF1MITF
	SCHEMBL23271796	0.77	MAPT (0.64)	ALDH1A1MAPTLMNAAPAF1MITF
	SCHEMBL30003449	0.77	MAPT (0.64)	ALDH1A1MAPTLMNAAPAF1MITF
	SCHEMBL496978	0.72	RAB9A (1.00)	ALDH1A1MAPTLMNAMITFRAB9A
	SCHEMBL3431641	0.72	RAB9A (0.59)	ALDH1A1MAPTRAB9ASMN1; SMN2NPC1
	SCHEMBL31441200	0.71	RAB9A (0.68)	ALDH1A1MAPTRAB9ASMN1; SMN2NPC1
	SCHEMBL27783998	0.71	RAB9A (0.50)	ALDH1A1MAPTLMNARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.