Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11403686 | 0.82 | HSD17B10 (0.52) | MTORTSHRHSD17B10NAPRTALDH1A1 | |
| SCHEMBL7258589 | 0.73 | HSD17B10 (0.60) | TSHRHSD17B10NAPRTALDH1A1NPSR1 | |
| SCHEMBL13149431 | 0.73 | ALDH1A1 (0.58) | MTORTSHRHSD17B10NAPRTALDH1A1 | |
| SCHEMBL11754900 | 0.73 | MTOR (0.72) | MTORHSD17B10NAPRTMEN1KMT2A | |
| SCHEMBL609888 | 0.73 | KMT2A (0.47) | TSHRNAPRTALDH1A1NPSR1KMT2A | |
| SCHEMBL7464419 | 0.72 | TSHR (0.47) | TSHRHSD17B10NAPRTALDH1A1NPSR1 | |
| SCHEMBL7471080 | 0.71 | RAB9A (0.50) | MTORTSHRHSD17B10NAPRTALDH1A1 | |
| SCHEMBL3067346 | 0.71 | EPHX2 (0.61) | TSHRHSD17B10NAPRTALDH1A1NPSR1 | |
| SCHEMBL12132227 | 0.71 | EPHX2 (0.61) | TSHRHSD17B10NAPRTALDH1A1NPSR1 | |
| SCHEMBL24777791 | 0.69 | MTOR (1.00) | MTORHSD17B10NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4966916-A | DI-AND TRIMETHYLAMINOETHYL BENZOATES, PHENYLCARBAMATES AND PHENYLTHIOCARBAMATES | UNIVERSITY OF ROCHESTER | 1990-10-30 | — | — | US | claimed |