Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471080 | 0.86 | RAB9A (0.50) | TSHRALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL11403686 | 0.78 | HSD17B10 (0.52) | TSHRALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL7469819 | 0.77 | NPC1 (0.50) | TSHRALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7376207 | 0.76 | AAK1 (0.64) | ALDH1A1LMNAHPGDMMEACE | |
| SCHEMBL7376209 | 0.76 | AAK1 (0.64) | ALDH1A1LMNAHPGDMMEACE | |
| Hydrochloric Acid SCHEMBL10788646 | 0.74 | AAK1 (0.62) | ALDH1A1LMNAHPGDMMEACE | |
| Acetic Acid SCHEMBL8935166 | 0.73 | AAK1 (0.61) | ALDH1A1LMNAMMEACETAAR1 | |
| SCHEMBL10401620 | 0.72 | MTOR (0.53) | TSHRALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL10789076 | 0.72 | LMNA (0.53) | TSHRLMNAHPGDMAPTLARS1 | |
| SCHEMBL16452816 | 0.71 | MME (0.61) | ALDH1A1LMNAHPGDNPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287605-A1 | AMINO-2 ETHANETHIOL DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1988-10-26 | — | — | EP | disclosed |
| WO-1988002363-A1 | AMINO-2 ETHANETHIOL DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M (FR) | 1988-04-07 | — | — | WO | disclosed |