Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401625 | 1.00 | MAPT (0.52) | MAPTMAPK1TDP1PTGS2ALDH1A1 | |
| SCHEMBL11132387 | 0.91 | MAPT (0.51) | MAPTMAPK1TDP1ALDH1A1MEN1 | |
| SCHEMBL5694459 | 0.90 | MAPT (0.53) | MAPTMAPK1TDP1ALDH1A1MEN1 | |
| SCHEMBL8973697 | 0.85 | MAPT (0.54) | MAPTMAPK1TDP1ALDH1A1MEN1 | |
| SCHEMBL13790265 | 0.85 | THRB (0.48) | THRATHRB | |
| SCHEMBL9570633 | 0.83 | MAPT (0.58) | MAPTMAPK1TDP1ALDH1A1MEN1 | |
| SCHEMBL10485355 | 0.83 | MAPT (0.45) | MAPTMAPK1TDP1ALDH1A1MEN1 | |
| SCHEMBL10485392 | 0.81 | THRA (0.48) | MAPTMAPK1TDP1ALDH1A1MEN1 | |
| SCHEMBL10497399 | 0.81 | MAPT (0.48) | MAPTMAPK1TDP1ALDH1A1MEN1 | |
| SCHEMBL10497408 | 0.81 | MAPT (0.48) | MAPTMAPK1TDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4937017-A | Nonlinear optically responsive inorganic-organic composite compositions | HOECHST CELANESE CORP. (US) | 1990-06-26 | — | — | US | disclosed |
| US-4887889-A | Organopolysiloxanes exhibiting nonlinear response | HOECHST CELANESE CORPORATION (US) | 1989-12-19 | — | — | US | disclosed |
| US-4885113-A | Nonlinear optically responsive inorganic-organic composite compositions | HOECHST CELANESE CORPORATION (US) | 1989-12-05 | — | — | US | disclosed |
| US-4855078-A | Organopolysiloxanes exhibiting nonlinear response | HOECHST CELANESE CORP. (US) | 1989-08-08 | — | — | US | disclosed |
| US-4807968-A | Polymer blends exhibiting nonlinear optical response | HOECHST CELANESE CORP. (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0304051-A2 | Nonlinear optically responsive inorganic-organic composite compositions | HOECHST CELANESE CORPORATION (US) | 1989-02-22 | — | — | EP | disclosed |
| US-4801659-A | Organopolysiloxanes exhibiting nonlinear optical response | HOECHST CELANESE CORP. (US) | 1989-01-31 | — | — | US | disclosed |