Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11132387 | 0.91 | MAPT (0.51) | MAPTALDH1A1POLBKCNH2THRA | |
| SCHEMBL5694459 | 0.90 | MAPT (0.53) | MAPTALDH1A1POLBKCNH2THRA | |
| SCHEMBL8973697 | 0.85 | MAPT (0.54) | MAPTALDH1A1POLBMGLLNPC1 | |
| SCHEMBL10300068 | 0.85 | THRB (0.48) | ALDH1A1KCNH2THRATHRBNPC1 | |
| SCHEMBL10401625 | 0.83 | MAPT (0.52) | MAPTALDH1A1POLBKCNH2THRA | |
| SCHEMBL9570633 | 0.83 | MAPT (0.58) | MAPTALDH1A1POLBMAPK1TDP1 | |
| SCHEMBL10401626 | 0.83 | MAPT (0.52) | MAPTALDH1A1POLBKCNH2THRA | |
| SCHEMBL10485392 | 0.81 | THRA (0.48) | MAPTALDH1A1POLBKCNH2THRA | |
| SCHEMBL10485905 | 0.80 | MAPT (0.55) | MAPTALDH1A1KCNH2MGLLNPC1 | |
| SCHEMBL8811170 | 0.78 | MAPT (0.58) | MAPTALDH1A1POLBMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4887889-A | Organopolysiloxanes exhibiting nonlinear response | HOECHST CELANESE CORPORATION (US) | 1989-12-19 | — | — | US | disclosed |
| US-4855078-A | Organopolysiloxanes exhibiting nonlinear response | HOECHST CELANESE CORP. (US) | 1989-08-08 | — | — | US | disclosed |
| US-4807968-A | Polymer blends exhibiting nonlinear optical response | HOECHST CELANESE CORP. (US) | 1989-02-28 | — | — | US | disclosed |
| US-4801659-A | Organopolysiloxanes exhibiting nonlinear optical response | HOECHST CELANESE CORP. (US) | 1989-01-31 | — | — | US | disclosed |