Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10401852 | 0.99 | CHRM4 (0.55) | CHRM4POLBKMT2ATSHRMEN1 | |
| Hydrochloric Acid SCHEMBL10401468 | 0.98 | CHRM4 (0.54) | CHRM4POLBKMT2ATSHRMEN1 | |
| SCHEMBL10401767 | 0.86 | SMN1; SMN2 (0.54) | MAPTSMN1; SMN2L3MBTL1GAAALDH1A1 | |
| SCHEMBL10401428 | 0.83 | NPC1 (0.62) | TSHRMAPTLMNAL3MBTL1GAA | |
| SCHEMBL10401826 | 0.82 | DRD2 (0.62) | POLBKMT2AMEN1MAPTLMNA | |
| SCHEMBL10401582 | 0.80 | TP53 (0.60) | CHRM4POLBKMT2AMEN1MAPT | |
| SCHEMBL10402030 | 0.78 | MEN1 (0.49) | CHRM4POLBKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL10401899 | 0.77 | MEN1 (0.48) | CHRM4POLBKMT2AMEN1MAPT | |
| SCHEMBL10402174 | 0.77 | NAMPT (0.60) | TSHRMAPTPANK3CYP2C9KDM4E | |
| SCHEMBL10401922 | 0.75 | MAPT (0.51) | POLBKMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960776-A | ANTIALLERGENS | A. H. ROBINS COMPANY, INC. (US) | 1990-10-02 | — | — | US | claimed |
| EP-0277725-A2 | 4-Aryl-N-[2-(dialkylamino and heterocyclicamino) alkyl]-1-piperazinecarboxamides and their use as anti allergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-08-10 | — | — | EP | claimed |