Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 6/20 | 0.52 |
| ▸ | DRD3 | P35462 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RBP4 | P02753 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401740 | 0.86 | CHRM4 (0.56) | SMN1; SMN2GAAL3MBTL1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL10401852 | 0.85 | CHRM4 (0.55) | SMN1; SMN2GAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL10401428 | 0.84 | NPC1 (0.62) | DRD2DRD3GAAL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL10401468 | 0.84 | CHRM4 (0.54) | SMN1; SMN2GAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL10401826 | 0.83 | DRD2 (0.62) | SMN1; SMN2DRD2DRD3GAAMAPT | |
| SCHEMBL10401849 | 0.81 | CHRM4 (0.54) | SMN1; SMN2DRD2MAPTAKR1C3DRD4 | |
| SCHEMBL10401384 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2DRD2DRD3MAPTALDH1A1 | |
| SCHEMBL10401770 | 0.80 | CHRM4 (0.57) | SMN1; SMN2MAPTALDH1A1HTR1AHTR2A | |
| SCHEMBL10402174 | 0.78 | NAMPT (0.60) | GAAMAPTALDH1A1 | |
| SCHEMBL5457584 | 0.77 | DRD2 (0.66) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960776-A | ANTIALLERGENS | A. H. ROBINS COMPANY, INC. (US) | 1990-10-02 | — | — | US | claimed |
| EP-0277725-A2 | 4-Aryl-N-[2-(dialkylamino and heterocyclicamino) alkyl]-1-piperazinecarboxamides and their use as anti allergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-08-10 | — | — | EP | claimed |
| US-4960776-A | ANTIALLERGENS | A. H. ROBINS COMPANY, INC. (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0277725-A2 | 4-Aryl-N-[2-(dialkylamino and heterocyclicamino) alkyl]-1-piperazinecarboxamides and their use as anti allergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-08-10 | — | — | EP | disclosed |